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FOXA1 Antikörper (AA 367-472)

Der Maus Monoklonal Anti-FOXA1-Antikörper wurde für WB, ELISA, IHC (p) und RNAi validiert. Er ist geeignet, FOXA1 in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.
Produktnummer ABIN561299

Kurzübersicht für FOXA1 Antikörper (AA 367-472) (ABIN561299)

Target

Alle FOXA1 Antikörper anzeigen
FOXA1 (Forkhead Box A1 (FOXA1))

Reaktivität

  • 169
  • 88
  • 39
  • 7
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 87
  • 82
  • 1
Maus

Klonalität

  • 112
  • 58
Monoklonal

Konjugat

  • 83
  • 10
  • 9
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FOXA1 Antikörper ist unkonjugiert

Applikation

  • 111
  • 92
  • 69
  • 64
  • 36
  • 36
  • 35
  • 20
  • 8
  • 8
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Klon

2D7
  • Bindungsspezifität

    • 46
    • 33
    • 12
    • 8
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 367-472

    Verwendungszweck

    Mouse monoclonal antibody raised against a partial recombinant FOXA1.

    Sequenz

    LASVPASHPA HGLAPHESQL HLKGDPHYSF NHPFSINNLM SSSEQQHKLD FKAYEQALQY SPYGSTLPAS LPLGSASVTT RSPIEPSALE PAYYQGVYSR PVLNTS

    Kreuzreaktivität

    Human

    Produktmerkmale

    Antibody Reactive Against Recombinant Protein.

    Immunogen

    FOXA1 (NP_004487, 367 a.a. ~ 472 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Isotyp

    IgG2a
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    In 1x PBS, pH 7.4

    Handhabung

    Aliquot to avoid repeated freezing and thawing.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Kobayashi, Iwaya, Moriya, Yamasaki, Tsuda, Yamamoto, Matsubara: "A simple immunohistochemical panel comprising 2 conventional markers, Ki67 and p53, is a powerful tool for predicting patient outcome in luminal-type breast cancer." in: BMC clinical pathology, Vol. 13, pp. 5, (2013) (PubMed).

    Braun, Mietzsch, Seibold, Schneeweiss, Schirmacher, Chang-Claude, Peter Sinn, Aulmann: "Intrinsic breast cancer subtypes defined by estrogen receptor signalling-prognostic relevance of progesterone receptor loss." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 9, pp. 1161-71, (2013) (PubMed).

    Jacquemier, Charafe-Jauffret, Monville, Esterni, Extra, Houvenaeghel, Xerri, Bertucci, Birnbaum: "Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer." in: Breast cancer research : BCR, Vol. 11, Issue 2, pp. R23, (2009) (PubMed).

    Bretschneider, Brand, Miller, Lowery, Kerin, Gannon, Denger: "Estrogen induces repression of the breast cancer and salivary gland expression gene in an estrogen receptor alpha-dependent manner." in: Cancer research, Vol. 68, Issue 1, pp. 106-14, (2008) (PubMed).

  • Target

    FOXA1 (Forkhead Box A1 (FOXA1))

    Andere Bezeichnung

    FOXA1

    Hintergrund

    Full Gene Name: forkhead box A1
    Synonyms: HNF3A,MGC33105,TCF3A

    Gen-ID

    3169

    NCBI Accession

    NM_004496

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis
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