DDR1 Antikörper (AA 21-176)

Produktnummer ABIN5611283

Dieses Maus Monoklonal-Antikörper erkennt spezifisch DDR1 in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DDR1 Antikörper (AA 21-176) (ABIN5611283)

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DDR1 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: 4F2C12

Produktdetails anti-DDR1 Antikörper

Bindungsspezifität: AA 21-176

Verwendungszweck: CD167 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD167 (AA: 21-176) expressed in E. Coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu DDR1

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Andere Bezeichnung: CD167

Hintergrund: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht: 101 kDa

UniProt: Q08345

Pathways: RTK Signalweg, Smooth Muscle Cell Migration