RUNX3 Antikörper (AA 294-429)
Kurzübersicht für RUNX3 Antikörper (AA 294-429) (ABIN5611280)
Target
Alle RUNX3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 294-429
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Verwendungszweck
- RUNX3 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human RUNX3 (AA: 294-429) expressed in E. Coli.
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Isotyp
- IgG2b
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/250
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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Andere Bezeichnung
- RUNX3
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Hintergrund
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This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.
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Molekulargewicht
- 44.4 kDa
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Gen-ID
- 864
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UniProt
- Q13761
Target
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