CTLA4 Antikörper (AA 36-161)

Produktnummer ABIN5611264

Dieses Anti-CTLA4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CTLA4 in FACS und ELISA. Geeignet für Human.

Kurzübersicht für CTLA4 Antikörper (AA 36-161) (ABIN5611264)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTLA4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA

Klon: 8B3F8

Produktdetails anti-CTLA4 Antikörper

Bindungsspezifität: AA 36-161

Verwendungszweck: CD152 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD152 (AA: 36-161) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CD152

Hintergrund: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Molekulargewicht: 24.6 kDa

Gen-ID: 1493

UniProt: P16410

Pathways: Cancer Immune Checkpoints