BCL6 Antikörper (AA 147-276)

Produktnummer ABIN5611253

Dieses Maus Monoklonal-Antikörper erkennt spezifisch BCL6 in FACS, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BCL6 Antikörper (AA 147-276) (ABIN5611253)

Target: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BCL6 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Klon: 2G1B6

Produktdetails anti-BCL6 Antikörper

Bindungsspezifität: AA 147-276

Verwendungszweck: BCL6 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human BCL6 (AA: 147-276) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu BCL6

Target: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Andere Bezeichnung: BCL6

Hintergrund: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Molekulargewicht: 78.8 kDa

UniProt: P41182

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus