PD-1 Antikörper (AA 21-170)

Produktnummer ABIN5611149

Der Maus Monoklonal Anti-PD-1-Antikörper wurde für FACS, ELISA und ICC validiert. Er ist geeignet, PD-1 in Proben von Human zu detektieren.

Kurzübersicht für PD-1 Antikörper (AA 21-170) (ABIN5611149)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PD-1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Klon: 3E12A10

Produktdetails anti-PD-1 Antikörper

Bindungsspezifität: AA 21-170

Verwendungszweck: PD1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human PD1 (AA: 21-170) expressed in HEK293 cells.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: PD1

Hintergrund: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Molekulargewicht: 31.6KD

Gen-ID: 5133

UniProt: Q15116

Pathways: Cancer Immune Checkpoints