FGFR2 Antikörper (AA 621-723)

Produktnummer ABIN560876

Der Maus Monoklonal Anti-FGFR2-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, FGFR2 in Proben von Human zu detektieren. Es sind 7+ Publikationen verfügbar.

Kurzübersicht für FGFR2 Antikörper (AA 621-723) (ABIN560876)

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGFR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1G3

Produktdetails anti-FGFR2 Antikörper

Bindungsspezifität: AA 621-723

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant FGFR2.

Sequenz: GHRMDKPANC TNELYMMMRD CWHAVPSQRP TFKQLVEDLD RILTLTTNEE YLDLSQPLEQ YSPSYPDTRS SCSSGDDSVF SPDPMPYEPC LPQYPHINGS VKT

Spezifität: This antibody cross-reacts with human FGFR1 and human FGFR3.

Kreuzreaktivität: Human

Kreuzreaktivität (Details): This antibody cross-reacts with human FGFR1 and human FGFR3.

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: FGFR2 (AAH39243, 621 a.a. ~ 723 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-FGFR2 Antikörper (ABIN560876)

Czaplinska, Mieczkowski, Supernat, Skladanowski, Kordek, Biernat, Zaczek, Romanska, Sadej: "Interactions between FGFR2 and RSK2-implications for breast cancer prognosis." in: Tumour biology, Vol. 37, Issue 10, pp. 13721-13731, (2016) (PubMed).

Katano, Yamada: "Upregulation of ANGPTL4 messenger RNA and protein in severely calcified carotid plaques." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 23, Issue 5, pp. 933-47, (2014) (PubMed).

Lee, Seo, Park, Kim, Park, Yu, Ahn, Gong: "Low prognostic implication of fibroblast growth factor family activation in triple-negative breast cancer subsets." in: Annals of surgical oncology, Vol. 21, Issue 5, pp. 1561-8, (2014) (PubMed).

Cazet, Charest, Bennett, Sambrooks, Contessa: "Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity." in: PLoS ONE, Vol. 9, Issue 10, pp. e110345, (2014) (PubMed).

Grygielewicz, Dymek, Bujak, Gunerka, Stanczak, Lamparska-Przybysz, Wieczorek, Dzwonek, Zdzalik: "Epithelial-mesenchymal transition confers resistance to selective FGFR inhibitors in SNU-16 gastric cancer cells." in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, (2014) (PubMed).

Ozawa, Yang, Ealy: "The expression of fibroblast growth factor receptors during early bovine conceptus development and pharmacological analysis of their actions on trophoblast growth in vitro." in: Reproduction (Cambridge, England), Vol. 145, Issue 2, pp. 191-201, (2013) (PubMed).

Vermeulen, Kornegoor, van der Wall, van der Groep, van Diest: "Differential expression of growth factor receptors and membrane-bound tumor markers for imaging in male and female breast cancer." in: PLoS ONE, Vol. 8, Issue 1, pp. e53353, (2013) (PubMed).

Details zu FGFR2

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Andere Bezeichnung: FGFR2

Hintergrund: Full Gene Name: fibroblast growth factor receptor 2
Synonyms: BEK,BFR-1,CD332,CEK3,CFD1,ECT1,FLJ98662,JWS,K-SAM,KGFR,TK14,TK25

Gen-ID: 2263

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding