CTH Antikörper (AA 1-405)

Produktnummer ABIN560522

Es sind 5+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-CTH Antikörper wird verwendet zum Nachweis von CTH in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für CTH Antikörper (AA 1-405) (ABIN560522)

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 2E12-1C10

Produktdetails anti-CTH Antikörper

Bindungsspezifität: AA 1-405

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant CTH.

Sequenz: MQEKDASSQG FLPHFQHFAT QAIHVGQDPE QWTSRAVVPP ISLSTTFKQG APGQHSGFEY SRSGNPTRNC LEKAVAALDG AKYCLAFASG LAATVTITHL LKAGDQIICM DDVYGGTNRY FRQVASEFGL KISFVDCSKI KLLEAAITPE TKLVWIETPT NPTQKVIDIE GCAHIVHKHG DIILVVDNTF MSPYFQRPLA LGADISMYSA TKYMNGRSDV VMGLVSVNCE SLHNRLRFLQ NSLGAVPSPI DCYLCNRGLK TLHVRMEKHF KNGMAVAQFL ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK NLKLFTLAES LGGFESLAEL PAIMTHASVL KNDRDVLGIS DTLIRLSVGL EDEEDLLEDL DQALKAAHPP SGSHS

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-CTH Antikörper (ABIN560522)

Grassi, Tyagi, Calvert, Gambari, Walker, Yu, Robinson, Li, Lisignoli, Vaccaro, Adams, Pacifici: "Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 5, pp. 949-63, (2016) (PubMed).

Dickhout, Carlisle, Jerome, Mohammed-Ali, Jiang, Yang, Mani, Garg, Banerjee, Kaufman, Maclean, Wang, Austin: "Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism." in: The Journal of biological chemistry, Vol. 287, Issue 10, pp. 7603-14, (2012) (PubMed).

Maclean, Sikora, Kožich, Jiang, Greiner, Kraus, Krijt, Overdier, Collard, Brodsky, Meltesen, Crnic, Allen, Stabler, Elleder, Rozen, Patterson, Kraus: "A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment." in: Molecular genetics and metabolism, Vol. 101, Issue 2-3, pp. 153-62, (2010) (PubMed).

dEmmanuele di Villa Bianca, Sorrentino, Maffia, Mirone, Imbimbo, Fusco, De Palma, Ignarro, Cirino: "Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 11, pp. 4513-8, (2009) (PubMed).

Zhang, Jiang, Fang, Yan, Song, Gupta, Schafer, Durante, Kruger, Yang, Wang: "Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine beta-synthase-deficient mice." in: Circulation, Vol. 120, Issue 19, pp. 1893-902, (2009) (PubMed).

Details zu CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Andere Bezeichnung: CTH

Hintergrund: Full Gene Name: cystathionase (cystathionine gamma-lyase)
Synonyms: MGC9471

Gen-ID: 1491

Pathways: ER-Nucleus Signaling, Warburg Effekt