CBS Antikörper (AA 1-551)

Produktnummer ABIN560204

Der Maus Polyklonal Anti-CBS-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CBS in Proben von Human zu detektieren. Es sind 11+ Publikationen verfügbar.

Kurzübersicht für CBS Antikörper (AA 1-551) (ABIN560204)

Target: CBS (Cystathionine-beta-Synthase (CBS))

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser CBS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CBS Antikörper

Bindungsspezifität: AA 1-551

Verwendungszweck: Mouse polyclonal antibody raised against a full-length recombinant CBS.

Sequenz: MPSETPQAEV GPTGCPHRSG PHSAKGSLEK GSPEDKEAKE PLWIRPDAPS RCTWQLGRPA SESPHHHTAP AKSPKILPDI LKKIGDTPMV RINKIGKKFG LKCELLAKCE FFNAGGSVKD RISLRMIEDA ERDGTLKPGD TIIEPTSGNT GIGLALAAAV RGYRCIIVMP EKMSSEKVDV LRALGAEIVR TPTNARFDSP ESHVGVAWRL KNEIPNSHIL DQYRNASNPL AHYDTTADEI LQQCDGKLDM LVASVGTGGT ITGIARKLKE KCPGCRIIGV DPEGSILAEP EELNQTEQTT YEVEGIGYDF IPTVLDRTVV DKWFKSNDEE AFTFARMLIA QEGLLCGGSA GSTVAVAVKA AQELQEGQRC VVILPDSVRN YMTKFLSDRW MLQKGFLKEE DLTEKKPWWW HLRVQELGLS APLTVLPTIT CGHTIEILRE KGFDQAPVVD EAGVILGMVT LGNMLSSLLA GKVQPSDQVG KVIYKQFKQI RLTDTLGRLS HILEMDHFAL VVHEQIQYHS TGKSSQRQMV FGVVTAIDLL NFVAAQERDQ K

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: CBS (AAH11381.1, 1 a.a. ~ 551 a.a) full-length recombinant protein with GST tag.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 50 % glycerol

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-CBS Antikörper (ABIN560204)

Grassi, Tyagi, Calvert, Gambari, Walker, Yu, Robinson, Li, Lisignoli, Vaccaro, Adams, Pacifici: "Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 5, pp. 949-63, (2016) (PubMed).

Martínez-Vega, Garrido, Partearroyo, Cediel, Zeisel, Martínez-Álvarez, Varela-Moreiras, Varela-Nieto, Pajares: "Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 2, pp. 418-32, (2015) (PubMed).

Kim, Lee, Lee, Park, Ryu: "Arsenite-induced changes in hepatic protein abundance in cynomolgus monkeys (Macaca fascicularis)." in: Proteomics, Vol. 14, Issue 15, pp. 1833-43, (2014) (PubMed).

Gupta, Wang, Anderl, Slifker, Kirk, Kruger: "Correction of cystathionine ?-synthase deficiency in mice by treatment with proteasome inhibitors." in: Human mutation, Vol. 34, Issue 8, pp. 1085-93, (2013) (PubMed).

Bhattacharyya, Saha, Giri, Lanza, Nair, Jennings, Rodriguez-Aguayo, Lopez-Berestein, Basal, Weaver, Visscher, Cliby, Sood, Bhattacharya, Mukherjee: "Cystathionine beta-synthase (CBS) contributes to advanced ovarian cancer progression and drug resistance." in: PLoS ONE, Vol. 8, Issue 11, pp. e79167, (2013) (PubMed).

Mayfield, Davies, Dimster-Denk, Pleskac, McCarthy, Boydston, Fink, Lin, Narain, Meighan, Rine: "Surrogate genetics and metabolic profiling for characterization of human disease alleles." in: Genetics, Vol. 190, Issue 4, pp. 1309-23, (2012) (PubMed).

Singh, Gupta, Honig, Kraus, Kruger: "Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70." in: PLoS genetics, Vol. 6, Issue 1, pp. e1000807, (2010) (PubMed).

Wu, Siow, O: "Ischemia/reperfusion reduces transcription factor Sp1-mediated cystathionine beta-synthase expression in the kidney." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18225-33, (2010) (PubMed).

Singh, Kruger: "Functional rescue of mutant human cystathionine beta-synthase by manipulation of Hsp26 and Hsp70 levels in Saccharomyces cerevisiae." in: The Journal of biological chemistry, Vol. 284, Issue 7, pp. 4238-45, (2009) (PubMed).

dEmmanuele di Villa Bianca, Sorrentino, Maffia, Mirone, Imbimbo, Fusco, De Palma, Ignarro, Cirino: "Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 11, pp. 4513-8, (2009) (PubMed).

Ali, Whiteman, Low, Moore: "Hydrogen sulphide reduces insulin secretion from HIT-T15 cells by a KATP channel-dependent pathway." in: The Journal of endocrinology, Vol. 195, Issue 1, pp. 105-12, (2007) (PubMed).

Details zu CBS

Target: CBS (Cystathionine-beta-Synthase (CBS))

Andere Bezeichnung: CBS

Hintergrund: Full Gene Name: cystathionine-beta-synthase
Synonyms: HIP4

Gen-ID: 875