Rekombinanter EIF4E Antikörper (pSer209)
Kurzübersicht für Rekombinanter EIF4E Antikörper (pSer209) (ABIN5557447)
Target
Alle EIF4E Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer209
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Verwendungszweck
- phospho-eIF4E (Ser209) Recombinant Antibody
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated Synthesised phosphopeptide derived from human EIF4E around the phosphorylation site of Ser209: SG(p-S)TT
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(1:50-200), ICC/IF(1:50-100)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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Andere Bezeichnung
- eIF4E
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Hintergrund
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Synonyms: CBP, EIF4F, AUTS19, EIF4E1, EIF4EL1, Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein
Background: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
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Gen-ID
- 1977
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UniProt
- P06730
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Pathways
- BCR Signaling
Target
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