Complement C3c Antikörper (AA 1521-1649)

Produktnummer ABIN5542705

Dieses Anti-Complement C3c-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Complement C3c in ELISA und IHC. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Complement C3c Antikörper (AA 1521-1649) (ABIN5542705)

Target: Complement C3c (C3C) (Complement Component C3c (C3C))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Complement C3c Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Klon: 8B5H2

Produktdetails anti-Complement C3c Antikörper

Bindungsspezifität: AA 1521-1649

Verwendungszweck: C3C Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human C3C (AA: 1521-1649) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Complement C3c Antikörper (ABIN5542705)

Helsby, Leader, Fenn, Gulsen, Bryant, Doughton, Sharpe, Whitley, Caunt, James, Pope, Kelly, Chalmers: "CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited." in: BMC cell biology, Vol. 15, pp. 6, (2014) (PubMed).

Details zu Complement C3c

Target: Complement C3c (C3C) (Complement Component C3c (C3C))

Andere Bezeichnung: C3C

Hintergrund: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.

Molekulargewicht: 187.1 kDa

Gen-ID: 718

UniProt: P01024