DDX39B Antikörper (AA 1-250)

Produktnummer ABIN5542645

Dieses Anti-DDX39B-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von DDX39B in ELISA, IHC, WB und ICC. Geeignet für Human und Maus.

Kurzübersicht für DDX39B Antikörper (AA 1-250) (ABIN5542645)

Target: DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DDX39B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC)

Klon: 2F5G7

Produktdetails anti-DDX39B Antikörper

Bindungsspezifität: AA 1-250

Verwendungszweck: DDX39B Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human DDX39B (AA: 1-250) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu DDX39B

Target: DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))

Andere Bezeichnung: DDX39B

Hintergrund: This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13 kDa, V1 subunit G2) gene.

Molekulargewicht: 49 kDa

Gen-ID: 7919

UniProt: Q13838

Pathways: Ribonucleoprotein Complex Subunit Organization