TCL1A Antikörper (AA 10-104)
Kurzübersicht für TCL1A Antikörper (AA 10-104) (ABIN5542543)
Target
Alle TCL1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 10-104
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Verwendungszweck
- TCL1A Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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Andere Bezeichnung
- TCL1A
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Hintergrund
- Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).
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Molekulargewicht
- 13.5 kDa
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Gen-ID
- 8115
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UniProt
- P56279
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Pathways
- Stem Cell Maintenance
Target
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