MITF Antikörper (AA 1-114)
Kurzübersicht für MITF Antikörper (AA 1-114) (ABIN5542529)
Target
Alle MITF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-114
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Verwendungszweck
- MITF Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human MITF (AA: 1-114) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- MITF (Microphthalmia-Associated Transcription Factor (MITF))
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Andere Bezeichnung
- MITF
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Hintergrund
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This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Molekulargewicht
- 58.8 kDa
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Gen-ID
- 4286
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UniProt
- O75030
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Pathways
- Chromatin Binding
Target
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