DNMT3B Antikörper (AA 1-150)

Produktnummer ABIN5542517

Dieses Maus Monoklonal-Antikörper erkennt spezifisch DNMT3B in ELISA, FACS und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DNMT3B Antikörper (AA 1-150) (ABIN5542517)

Target: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DNMT3B Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 4D1A2E5

Produktdetails anti-DNMT3B Antikörper

Bindungsspezifität: AA 1-150

Verwendungszweck: DNMT3B Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human DNMT3B (AA: 1-150) expressed in E. Coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu DNMT3B

Target: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Andere Bezeichnung: DNMT3B

Hintergrund: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Molekulargewicht: 95.8 kDa

Gen-ID: 1789

UniProt: Q9UBC3