DNMT3B Antikörper (AA 389-417)
Kurzübersicht für DNMT3B Antikörper (AA 389-417) (ABIN3030752)
Target
Alle DNMT3B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 389-417
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Verwendungszweck
- Dnmt3b Antibody
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 389-417 from the human protein was used as the immunogen for this Dnmt3b antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the Dnmt3b antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Dnmt3b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
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Andere Bezeichnung
- Dnmt3b
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Hintergrund
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3b is a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF)syndrome.
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UniProt
- Q9UBC3
Target
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