PSG1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Flow cytometry: 1.2 μg/10e6 cells.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Phosphate buffered saline, pH 7.2
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
PSG1
(Pregnancy Specific beta-1-Glycoprotein 1 (PSG1))
Andere Bezeichnung
cd66f,psg1
Hintergrund
The human pregnancy-specific glycoprotein family (PSG) is a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin (1). PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarci-noma). They represent the most abundant fetal protein in the maternal blood at term. Together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes, the human PSG genes form the CEACAM gene family (2). PSG stimulate secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17 (3). PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection (4).