MMP17 Antikörper

Produktnummer ABIN5542064

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MMP17 in EIA und Neut. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MMP17 Antikörper (ABIN5542064)

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MMP17 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Neutralization (Neut)

Klon: 12N24

Produktdetails anti-MMP17 Antikörper

Spezifität: This antibody recognizes Human MMP-17 by direct ELISA.

Aufreinigung: Protein G Chromatography

Immunogen: Recombinant Human MMP-17

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1000-1/2000. Neutralization.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Sterile PBS

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu MMP17

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Andere Bezeichnung: mmp-17

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage and is known to be expressed in brain, leukocytes, colon, ovary testis and breast cancer as well as in many transformed and non-transformed cell types. The protein exists in two isoforms: a GPI-anchored form and a second secreted form.

UniProt: Q9ULZ9