CD27 Antikörper

Produktnummer ABIN5541980

Dieser Hamster Monoklonal Antikörper detektiert spezifisch CD27 in FACS, IHC (p), IHC (fro) und Func. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für CD27 Antikörper (ABIN5541980)

Target: CD27 (CD27 Molecule (CD27))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD27 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Klon: LG-3A10

Produktdetails anti-CD27 Antikörper

Spezifität: Recognizes Mouse CD27 receptor.

Aufreinigung: Protein G Chromatography

Immunogen: MCD27 tag expressing clones AR0524 and AR0530 from Armenian Hamster spleen.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Functional Studies (stimulating). Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: This clone (LG.3A10) has been reported to work on Paraffin tissue sections.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS Preservatives: None

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD27

Target: CD27 (CD27 Molecule (CD27))

Andere Bezeichnung: cd27

Hintergrund: CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both αβ and γδ T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.

UniProt: P41272

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints