LGR4 Antikörper
Kurzübersicht für LGR4 Antikörper (ABIN5541954)
Target
Alle LGR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes LGR4 / GPR48. Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.
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Aufreinigung
- Affinity Chromatography on Protein G
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Immunogen
- cDNA encoding Human LGR4
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Isotyp
- IgG2a
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Applikationshinweise
- Flow cytometry: 1.2 μg/10 6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.2
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Haltbarkeit
- 12 months
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- LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
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Andere Bezeichnung
- lgr4,gpr48
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Hintergrund
- LGR4 (Leucine-rich repeat- containing G protein-coupled receptor 4) belongs to the superfamily of G protein-coupled receptors (GPCRs). It is a 951 amino acid multi-pass membrane protein and has multiple N-terminal leucine-rich repeats, which are important for interaction with the glycoprotein ligands, and 7 transmembrane domains (1,3). LGR4 is highly expressed in the adult human pancreas but also with moderate levels of expression in placenta, kidney, brain and heart (2). LGR4 functions as an orphan receptor that may be involved in physiologic activities throughout the cell. It is overexpressed in various cancer types and is thought to enhance carcinoma invasiveness and metastasis, suggesting an important role in tumor progression.
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UniProt
- Q9BXB1
Target
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