Ficolin 2 Antikörper (Biotin)

Produktnummer ABIN5541920

Dieser Maus Monoklonal Antikörper detektiert spezifisch Ficolin 2 in IP und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Ficolin 2 Antikörper (Biotin) (ABIN5541920)

Target: Ficolin 2 (FCN2) (Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ficolin 2 Antikörper ist konjugiert mit Biotin

Applikation: Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Klon: GN4

Produktdetails anti-Ficolin 2 Antikörper (Biotin)

Spezifität: The monoclonal antibody GN4 recognizes L-Ficolin/P35.

Immunogen: L-Ficolin/P35 isolated from Human plasma

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immuno Assays. Immunoprecipitation. For Western blot of Non-Reduced samples we advise to use AM32978PU-N (Clone GN5).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Ficolin 2

Target: Ficolin 2 (FCN2) (Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2))

Andere Bezeichnung: ficolin-2

Hintergrund: Ficolins are a group of proteins containing both a collagen-like domain and a fibrinogen-like domain. They are found in various tissues. The domain organizations between ficolins and mannose binding lectin (MBL) are similar, although the carbohydrate-binding moieties are different. In man two types of ficolins (Lficolin/ P35 and H-ficolin) are present in serum and one type (M-ficolin) in cells. L-ficolin/P35 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between L-ficolin/P35 and MASPs/sMAP is Ca 2+ -dependent. MASPs in L-ficolin/P35-MASP complexes have proteolytic activities for C4, C2 and C3. L-ficolin/P35 also shows opsonic activity.

UniProt: Q15485

Pathways: Komplementsystem