ACE2 Antikörper (C-Term, Extracellular Domain)

Produktnummer ABIN5541562

Der Maus Monoklonal anti-ACE2 Antikörper (Klon 11A31) (ABIN5541562) detektiert spezifisch ACE2 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ACE2 Antikörper (C-Term, Extracellular Domain) (ABIN5541562)

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ACE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 11A31

Produktdetails anti-ACE2 Antikörper

Bindungsspezifität: C-Term, Extracellular Domain

Spezifität: This antibody was selected for its ability to detect ACE-2. Species: Human.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Human ACE-2 recombinant protein (extracellular domain).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Sterile PBS

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu ACE2

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Andere Bezeichnung: ace2

Hintergrund: The protein encoded by the gene ACE belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour