Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TEP1 Antikörper (N-Term)

This anti-TEP1 antibody (ABIN5541415) is a Rabbit Polyclonal antibody detecting TEP1 in WB, IHC (p). Suitable for Human, Mouse, Rat.
Produktnummer ABIN5541415

Kurzübersicht für TEP1 Antikörper (N-Term) (ABIN5541415)

Target

Alle TEP1 Antikörper anzeigen
TEP1 (Telomerase-Associated Protein 1 (TEP1))

Reaktivität

Human, Maus, Ratte

Wirt

  • 1
  • 1
Kaninchen

Klonalität

  • 1
  • 1
Polyklonal

Konjugat

  • 2
Dieser TEP1 Antikörper ist unkonjugiert

Applikation

  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    N-Term

    Spezifität

    Species: Human, Mouse and Rat.

    Aufreinigung

    Immunoaffinity Chromatography.

    Immunogen

    Synthetic Peptide corresponding to 20 Amino Acid peptide from near the amino terminus of human TP1.
  • Applikationshinweise

    Immunohistochemistry on Paraffin Sections (5 μg/mL). Western Blot.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Dilute only prior to immediate use. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    Haltbarkeit

    12 months
  • Target

    TEP1 (Telomerase-Associated Protein 1 (TEP1))

    Andere Bezeichnung

    tep1,tlp1

    Hintergrund

    Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TEP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TEP1 do not correlate with malignancy. At least two isoforms of TP1 are known to exist.

    UniProt

    Q99973

    Pathways

    Inositol Metabolic Process, Synaptic Membrane, Regulation of Cell Size, Autophagie, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor
Sie sind hier:
Chat with us!