FUBP1 Antikörper (AA 279-448)

Produktnummer ABIN5541255

Der Maus Monoklonal Anti-FUBP1-Antikörper wurde für WB, IF, ICC und EIA validiert. Er ist geeignet, FUBP1 in Proben von Human zu detektieren.

Kurzübersicht für FUBP1 Antikörper (AA 279-448) (ABIN5541255)

Target: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FUBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)

Klon: AT14F5

Produktdetails anti-FUBP1 Antikörper

Bindungsspezifität: AA 279-448

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human FUBP1 (279-448aa) purified from E.coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu FUBP1

Target: FUBP1 (Far Upstream Element (FUSE) Binding Protein 1 (FUBP1))

Andere Bezeichnung: fubp1

Hintergrund: FUBP1 is a transcriptiol regulator and fulfills an important function in the precise control of c-myc transcription. The c-Myc protein is a transcription factor which regulates the transcription of many different target genes that play a role in proliferation, cell cycle progression, differentiation, apoptosis and cell metabolism. Consequently, FUBP1 is also involved in the regulation of proliferation and differentiation, as confirmed by different experimental approaches. Knockdown of FUBP1 or expression of a domint-negative FUBP1 (D-binding domain lacking effector activity) led to proliferation arrest in U2OS and Saos-2 osteosarcoma cells due to reduced c-myc expression.

UniProt: Q96AE4