TERT Antikörper (AA 627-656)

Produktnummer ABIN5540961

Der Kaninchen Polyklonal anti-TERT Antikörper wird verwendet zum Nachweis von TERT in Proben von Human. Er wurde validiert für WB, FACS, IF, ICC und IHC (p).

Kurzübersicht für TERT Antikörper (AA 627-656) (ABIN5540961)

Target: TERT (Telomerase Reverse Transcriptase (TERT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TERT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TERT Antikörper

Bindungsspezifität: AA 627-656

Spezifität: This antibody detects Human TERT at center. Other species not tested.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: KLH conjugated synthetic peptide selected from the Center region of Human TERT.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 1/10-1/50. Western blot: 1/1000, Flow Cytometry: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/100.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS Preservatives: 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu TERT

Target: TERT (Telomerase Reverse Transcriptase (TERT))

Andere Bezeichnung: tert

Hintergrund: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.

UniProt: O14746

Pathways: Telomere Maintenance