SRY
Reaktivität: Human
WB, ELISA, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Western blot: 1-5 μg/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
SRY
(Sex Determining Region Y (SRY))
Andere Bezeichnung
sry,tdf
Hintergrund
The "Sex determining region of Y-Gen" (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor). It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex.