RanBP3 Antikörper (AA 235-445)

Produktnummer ABIN5540644

Der Maus Monoklonal anti-RanBP3 Antikörper (Klon AT12E11) (ABIN5540644) detektiert spezifisch RanBP3 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RanBP3 Antikörper (AA 235-445) (ABIN5540644)

Target: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RanBP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT12E11

Produktdetails anti-RanBP3 Antikörper

Bindungsspezifität: AA 235-445

Spezifität: Recognizes Human RANBP3. Other species not tested.

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human RANBP3 (235-445aa) purified from E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu RanBP3

Target: RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Andere Bezeichnung: ranbp3

Hintergrund: The GTPase Ran is a small protein that belongs to the RAS protein superfamily and is found associated with the nuclear membrane. Ran GTPase is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. Ran binding proteins (RanBPs) belong to a family of proteins that bind Ran GTPase and help to stimulate its GTPase activity. Members of the RanBP family show weak similarity to importin beta, a protein involved in the transport of proteins to the nuclear membrane. Recently it has been shown that RanBP3 function is regulated by the Ras/ERK/RSK and PI3K/Akt signaling pathway. This finding has provided a link between nuclear transport, cell signaling, and cell fate.

UniProt: Q9H6Z4