NCOA1 Antikörper (pSer75)
Kurzübersicht für NCOA1 Antikörper (pSer75) (ABIN5540512)
Target
Alle NCOA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer75
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Spezifität
- The antibody detects endogenous level of Src only when phosphorylated at serine 75.
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Aufreinigung
- Affinity chromatography using epitope-specific peptide
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Immunogen
- Peptide sequence around phosphorylation site of serine 75 (V-T-S(p)-P-Q) derived from Human Src (KLH-conjugated)
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Applikationshinweise
- Western blot: 1:500~1:1000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Haltbarkeit
- 12 months
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- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
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Andere Bezeichnung
- src1
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Hintergrund
- Proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme.
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UniProt
- P12931
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
Target
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