Cathepsin S Antikörper (AA 17-331)

Produktnummer ABIN5540225

Dieser Maus Monoklonal Antikörper detektiert spezifisch Cathepsin S in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Cathepsin S Antikörper (AA 17-331) (ABIN5540225)

Target: Cathepsin S (CTSS)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cathepsin S Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT1F9

Produktdetails anti-Cathepsin S Antikörper

Bindungsspezifität: AA 17-331

Spezifität: This antibofy recognizes Human CTSS. Other species not tested.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Recombinant human CTSS (17-331aa) purified from E. coli

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution: 1/500.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Cathepsin S

Target: Cathepsin S (CTSS)

Andere Bezeichnung: cathepsin s

Hintergrund: CTSS (Cathepsin S) is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, CTSS is expressed in some epithelial cells. In contrast, cortical thymic epithelial cells do not express CTSS. Normal epidermal keratinocytes do not express CTSS. However, level of CTSS is elevated in psoriatic keratinocytes due to stimulation by proinflammatory factors. CTSS can function as an elastase over a broad pH range in alveolar macrophages.

UniProt: P25774

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades