Chromogranin A Antikörper

Produktnummer ABIN5540207

Dieser Maus Monoklonal Antikörper detektiert spezifisch Chromogranin A in FACS und EIA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Chromogranin A Antikörper (ABIN5540207)

Target: Chromogranin A (CHGA)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Chromogranin A Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: NJ-5C9

Produktdetails anti-Chromogranin A Antikörper

Spezifität: Recognizes Chromogranin A (CGA).

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Genetic immunisation with cDNA encoding CGA

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1.2 μg/10e6 cells. ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Chromogranin A

Target: Chromogranin A (CHGA)

Andere Bezeichnung: chromogranin a

Hintergrund: Chromogranin A (CgA) is a 49 kDa protein which is a member of the granin/secretogranin family of acidic glycoproteins. It is specifically expressed in all endocrine and neuroendocrine cells and plays multiple roles in the process of regulated secretion of peptide hormones and neurotransmitters (1). Owing to its over-expression in several tumors of neuroendocrine origin, CgA is of diagnostic value in classical endocrine, in hormone-negative and in neuroendocrine tumors (2).

UniProt: P10645

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling