TEK Antikörper (PE)

Produktnummer ABIN5540122

Dieses Anti-TEK-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TEK in FACS. Geeignet für Human.

Kurzübersicht für TEK Antikörper (PE) (ABIN5540122)

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TEK Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: Cl-16

Produktdetails anti-TEK Antikörper (PE)

Spezifität: The unconjugated monoclonal antibody will detect native human TIE-2 /TEK in ELISA experiments and on the surface of different human cell types. Species: Human.

Aufreinigung: Protein G Chromatography

Immunogen: Recombinant human soluble CD202b / TIE-2 protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: FACS analysis and cell sorting: ≤ 0.5 μg/mL in 100 μL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu TEK

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Andere Bezeichnung: cd202b,tek

Hintergrund: TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.

UniProt: Q02763

Pathways: RTK Signalweg, Growth Factor Binding