TEK Antikörper (FITC)
Kurzübersicht für TEK Antikörper (FITC) (ABIN5540120)
Target
Alle TEK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The unconjugated monoclonal antibody will detect native human TIE-2 /TEK in ELISA experiments and on the surface of different human cell types. Species: Human.
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Aufreinigung
- Protein G Chromatography
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Immunogen
- Recombinant human soluble CD202b / TIE-2 protein
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Isotyp
- IgG1
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Applikationshinweise
- FACS analysis and cell sorting: ≤ 0.5 μg/mL in 100 μL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.
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Haltbarkeit
- 12 months
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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Andere Bezeichnung
- cd202b,tek
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Hintergrund
- TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.
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UniProt
- Q02763
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Pathways
- RTK Signalweg, Growth Factor Binding
Target
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