C3 Antikörper

Produktnummer ABIN5540070

Der Kaninchen Polyklonal Anti-C3-Antikörper wurde für FACS validiert. Er ist geeignet, C3 in Proben von Schwein zu detektieren.

Kurzübersicht für C3 Antikörper (ABIN5540070)

Target: C3 (Complement Component 3 (C3))

Reaktivität: Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C3 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Produktdetails anti-C3 Antikörper

Spezifität: The polyclonal antibody recognizes Pig complement component C3.

Aufreinigung: Purified

Immunogen: Purified Pig C3

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 1/50 as a typical starting working dilution. Positive Control: Red Blood Cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.02 % Sodium Azide Stabilizers: 0.1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu C3

Target: C3 (Complement Component 3 (C3))

Andere Bezeichnung: complement c3

Hintergrund: The complement system is an important part of the humoral response in innate immunity, consisting of three different pathways. The third complement component, C3, is central to the classical, alternative and lectin pathways of complement activation. Activation products of the complement cascade contain neo-epitopes that are not present in the individual native components. The complement factor C3 consists of an alpha- and a beta-chain. The synthesis of C3 is tissue-specific and is modulated in response to a variety of stimulatory agents. C3 is the most abundant protein of the complement system with serum protein levels of about 1.3 mg/mL. An inherited deficiency of C3 predisposes the person to frequent assaults of bacterial infections. In ulcerative colitis, and idiopathic chronic inflammatory bowel disease, the deposition of C3 in the diseased mucosa has been reported. Proteolysis by certain enzymes results in the cleavage of C3 into C3a and C3b. C3b becomes attached to immune complexes and is further cleaved into iC3b, C3c, C3dg and C3f.

UniProt: P01025

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling