SYK Antikörper (AA 195-223)
Kurzübersicht für SYK Antikörper (AA 195-223) (ABIN5536407)
Target
Alle SYK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 195-223
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This Mouse Syk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of mouse Syk.
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Isotyp
- Ig Fraction
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anti-Spleen tyrosine Kinase (SYK) (AA 5-360) antibody
SYK Reaktivität: Human, Maus, Ratte WB, IP, IHC (p), ICC Wirt: Maus Monoclonal SYK-01 unconjugated
anti-Spleen tyrosine Kinase (SYK) (Internal Region) antibodySYK Reaktivität: Human, Maus, Ratte WB, IF, IP, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr525) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr348) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr323) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibodySYK Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 2G11E6 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibodySYK Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 3D1G10 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 387-417), (C-Term) antibodySYK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB03097 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 374-635) antibodySYK Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr525), (pTyr526) antibodySYK Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- For WB starting dilution is: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SYK (Spleen tyrosine Kinase (SYK))
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Andere Bezeichnung
- Syk
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Hintergrund
- Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion. Phosphorylates USP25 and regulates its intracellular levels (By similarity).
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Molekulargewicht
- 71 kDa
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Gen-ID
- 20963
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UniProt
- P48025
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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