ORC2 Antikörper (AA 208-237)

Produktnummer ABIN5534578

Dieses Anti-ORC2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ORC2 in WB. Geeignet für Human.

Kurzübersicht für ORC2 Antikörper (AA 208-237) (ABIN5534578)

Target: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ORC2 Antikörper

Bindungsspezifität: AA 208-237

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ORC2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human ORC2L.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ORC2

Target: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Andere Bezeichnung: ORC2L

Hintergrund: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.

Molekulargewicht: 66 kDa

Gen-ID: 4999

UniProt: Q13416