EPO Antikörper (AA 329-357)

Produktnummer ABIN5533603

Produktdetails anti-EPO Antikörper

Target: EPO (Erythropoietin (EPO))

Bindungsspezifität: AA 329-357

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EPOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human EPOR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu EPO

Target: EPO (Erythropoietin (EPO))

Andere Bezeichnung: EPO (EPO Produkte)

Synonyme: EPO antikoerper, EP antikoerper, MVCD2 antikoerper, erythropoietin antikoerper, erythropoietin S homeolog antikoerper, erythropoietin a antikoerper, EPO antikoerper, epo antikoerper, epo.S antikoerper, Epo antikoerper, epoa antikoerper

Substanzklasse: Hormone

Hintergrund: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 55 kDa

Gen-ID: 2057

UniProt: P19235

Pathways: JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity