Stanniocalcin 1 Antikörper (C-Term)
Kurzübersicht für Stanniocalcin 1 Antikörper (C-Term) (ABIN5532152)
Target
Alle Stanniocalcin 1 (STC1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 193-221, C-Term
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This STC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-221 amino acids from the C-terminal region of human STC1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- For WB starting dilution is: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Stanniocalcin 1 (STC1)
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Andere Bezeichnung
- STC1
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Hintergrund
- This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
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Molekulargewicht
- 28 kDa
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Gen-ID
- 6781
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UniProt
- P52823
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Pathways
- Hormone Activity
Target
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