PCDHA4 Antikörper (C-Term)

Produktnummer ABIN5531976

Der Kaninchen Polyklonal Anti-PCDHA4-Antikörper wurde für WB validiert. Er ist geeignet, PCDHA4 in Proben von Human zu detektieren.

Kurzübersicht für PCDHA4 Antikörper (C-Term) (ABIN5531976)

Target: PCDHA4 (Protocadherin alpha 4 (PCDHA4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PCDHA4 Antikörper

Bindungsspezifität: AA 761-790, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 761-790 amino acids from the C-terminal region of human PCDHA4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PCDHA4

Target: PCDHA4 (Protocadherin alpha 4 (PCDHA4))

Andere Bezeichnung: PCDHA4

Hintergrund: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Molekulargewicht: 102 kDa

Gen-ID: 56144

UniProt: Q9UN74