MCPH1 Antikörper (N-Term)

Produktnummer ABIN5531653

Der Kaninchen Polyklonal anti-MCPH1 Antikörper (ABIN5531653) detektiert spezifisch MCPH1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MCPH1 Antikörper (N-Term) (ABIN5531653)

Target: MCPH1 (Microcephalin 1 (MCPH1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCPH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MCPH1 Antikörper

Bindungsspezifität: AA 104-133, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human MCPH1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu MCPH1

Target: MCPH1 (Microcephalin 1 (MCPH1))

Andere Bezeichnung: MCPH1

Hintergrund: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

Molekulargewicht: 93 kDa

Gen-ID: 79648

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance