MCPH1 Antikörper (AA 60-140)

Produktnummer ABIN7225086

Der Kaninchen Polyklonal anti-MCPH1 Antikörper wird verwendet zum Nachweis von MCPH1 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für MCPH1 Antikörper (AA 60-140) (ABIN7225086)

Target: MCPH1 (Microcephalin 1 (MCPH1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCPH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MCPH1 Antikörper

Bindungsspezifität: AA 60-140

Verwendungszweck: Rabbit Anti-Microcephalin Polyclonal Antibody

Spezifität: Microcephalin Polyclonal Antibody detects endogenous levels of Microcephalin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Microcephalin at AA range: 60-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MCPH1

Target: MCPH1 (Microcephalin 1 (MCPH1))

Andere Bezeichnung: Microcephalin

Hintergrund: MCPH1, MicrocephalinMCPH1 (microcephalin 1) encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in MCPH1 have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

Molekulargewicht: 93kD

Gen-ID: 79648

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance