EIF3C Antikörper (AA 538-566)

Produktnummer ABIN5531093

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch EIF3C in WB. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für EIF3C Antikörper (AA 538-566) (ABIN5531093)

Target: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF3C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EIF3C Antikörper

Bindungsspezifität: AA 538-566

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EIF3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 538-566 amino acids from the Central region of human EIF3C.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu EIF3C

Target: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Andere Bezeichnung: EIF3C

Hintergrund: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Molekulargewicht: 105 kDa

Gen-ID: 8663

UniProt: Q99613

Pathways: Ribonucleoprotein Complex Subunit Organization