PCGF2 Antikörper (AA 121-150)

Produktnummer ABIN5531018

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PCGF2 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PCGF2 Antikörper (AA 121-150) (ABIN5531018)

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCGF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PCGF2 Antikörper

Bindungsspezifität: AA 121-150

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human PCGF2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.49 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PCGF2

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Andere Bezeichnung: PCGF2

Hintergrund: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

Molekulargewicht: 38 kDa

Gen-ID: 7703

UniProt: P35227

Pathways: Chromatin Binding