COPZ1 Antikörper (N-Term)

Produktnummer ABIN5530937

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch COPZ1 in WB. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für COPZ1 Antikörper (N-Term) (ABIN5530937)

Target: COPZ1 (Coatomer Protein Complex, Subunit zeta 1 (COPZ1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPZ1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COPZ1 Antikörper

Bindungsspezifität: AA 24-53, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COPZ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human COPZ1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu COPZ1

Target: COPZ1 (Coatomer Protein Complex, Subunit zeta 1 (COPZ1))

Andere Bezeichnung: COPZ1

Hintergrund: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

Molekulargewicht: 20 kDa

Gen-ID: 22818

UniProt: P61923