SAG Antikörper (AA 193-405)

Produktnummer ABIN5519058

Produktdetails anti-SAG Antikörper

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Bindungsspezifität: AA 193-405

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Rabbit IgG polyclonal antibody for Retinal S antigen detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Retinal S antigen detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
Gene Name: S-antigen visual arrestin
Protein Name: S-arrestin

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived huamn Retinal S antigen recombinant protein (Position: R193-E405).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu SAG

Target: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Andere Bezeichnung: SAG (SAG Produkte)

Synonyme: RP47 antikoerper, S-AG antikoerper, MGC75721 antikoerper, MGC84416 antikoerper, sag antikoerper, zgc:114197 antikoerper, SAGMR antikoerper, SANTI antikoerper, ARR antikoerper, sag1 antikoerper, A930001K18Rik antikoerper, Arr1 antikoerper, Irbp antikoerper, arrestin antikoerper, S-antigen visual arrestin antikoerper, S-antigen antikoerper, S-antigen; retina and pineal gland (arrestin) antikoerper, S-antigen; retina and pineal gland (arrestin) S homeolog antikoerper, S-antigen; retina and pineal gland (arrestin) b antikoerper, S-antigen, retina and pineal gland (arrestin) antikoerper, S-antigen; retina and pineal gland (arrestin) L homeolog antikoerper, SAG antikoerper, PF10_0343 antikoerper, sag antikoerper, sag.S antikoerper, sagb antikoerper, Sag antikoerper, sag.L antikoerper

Hintergrund: S-arrestin is a protein that in humans is encoded by the SAG gene. Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.

Synonyms: S-arrestin, 48 kDa protein, Retinal S-antigen, S-AG, Rod photoreceptor arrestin, SAG

Gen-ID: 6295

UniProt: P10523

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling