Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

MED20 Antikörper (AA 1-212)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MED20 in ELISA und WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.
Produktnummer ABIN5519037

Kurzübersicht für MED20 Antikörper (AA 1-212) (ABIN5519037)

Target

Alle MED20 Antikörper anzeigen
MED20 (Mediator Complex Subunit 20 (MED20))

Reaktivität

  • 10
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 8
  • 2
Kaninchen

Klonalität

  • 10
Polyklonal

Konjugat

  • 7
  • 1
  • 1
  • 1
Dieser MED20 Antikörper ist unkonjugiert

Applikation

  • 6
  • 5
  • 2
  • 1
  • 1
ELISA, Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 1
    • 1
    • 1
    AA 1-212

    Verwendungszweck

    Anti-TRFP/MED20 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-TRFP/MED20 Antibody Picoband® (ABIN5519037). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived human TRFP / MED20 recombinant protein (Position: M1-R212).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Sato, S., Tomomori-Sato, C., Banks, C. A. S., Parmely, T. J., Sorokina, I., Brower, C. S., Conaway, R. C., Conaway, J. W. A mammalian homolog of Drosophila melanogaster transcriptional coactivator Intersex is a subunit of the mammalian Mediator complex. J. Biol. Chem. 278: 49671-49674, 2003. 2. Xiao, H., Tao, Y., Roeder, R. G. The human homologue of Drosophila TRF-proximal protein is associated with an RNA polymerase II-SRB complex. J. Biol. Chem. 274: 3937-3940, 1999.

    Kommentare

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    MED20 (Mediator Complex Subunit 20 (MED20))

    Andere Bezeichnung

    MED20

    Hintergrund

    Synonyms: Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20, TRF-proximal protein homolog, hTRFP, MED20, TRFP,

    Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

    Background: MED20 is a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder.

    Molekulargewicht

    23 kDa

    Gen-ID

    9477

    UniProt

    Q9H944

    Pathways

    Regulation of Lipid Metabolism by PPARalpha
Sie sind hier:
Chat with us!