MED20 Antikörper (AA 60-140)

Produktnummer ABIN7229624

Der Kaninchen Polyklonal anti-MED20 Antikörper wird verwendet zum Nachweis von MED20 in Proben von Human, Ratte und Maus. Er wurde validiert für ELISA und WB.

Kurzübersicht für MED20 Antikörper (AA 60-140) (ABIN7229624)

Target: MED20 (Mediator Complex Subunit 20 (MED20))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED20 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-MED20 Antikörper

Bindungsspezifität: AA 60-140

Verwendungszweck: Rabbit Anti-MED20 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MED20 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MED20 protein at AA range: 60-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MED20

Target: MED20 (Mediator Complex Subunit 20 (MED20))

Andere Bezeichnung: MED20

Hintergrund: Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20, TRF-proximal protein homolog, hTRFPMED20 encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder. Alternatively spliced transcript variants have been identified.

Molekulargewicht: 23kD

Gen-ID: 9477

UniProt: Q9H944

Pathways: Regulation of Lipid Metabolism by PPARalpha