IL12B Antikörper (AA 23-250)

Produktnummer ABIN5519010

Produktdetails anti-IL12B Antikörper

Target: IL12B (Interleukin 12 beta (IL12B))

Bindungsspezifität: AA 23-250

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL12B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for IL12B detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for IL12B detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.
Gene Name: interleukin 12B
Protein Name: Interleukin-12 subunit beta

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived rat IL12B recombinant protein (Position: M23-E250).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-IL12B Antikörper (ABIN5519010)

Dong, Xia, Chen, Chen, Zhang: "Anti-arthritis activity of cationic materials." in: Journal of cellular and molecular medicine, Vol. 14, Issue 7, pp. 2015-24, (2011) (PubMed).

Details zu IL12B

Target: IL12B (Interleukin 12 beta (IL12B))

Andere Bezeichnung: Il12b (IL12B Produkte)

Synonyme: CLMF antikoerper, CLMF2 antikoerper, IL-12B antikoerper, NKSF antikoerper, NKSF2 antikoerper, p40 antikoerper, Il-12b antikoerper, Il12p40 antikoerper, Il-12p40 antikoerper, Il12 antikoerper, IL-12p40 antikoerper, IL-12 antikoerper, IL-12 p40 antikoerper, il12b antikoerper, il12p40.b antikoerper, zgc:152789 antikoerper, IL-12.p40 antikoerper, IL12p40 antikoerper, IL12B antikoerper, CLMF p40 antikoerper, interleukin 12B antikoerper, interleukin 12b antikoerper, interleukin 12Ba antikoerper, IL12B antikoerper, Il12b antikoerper, il12ba antikoerper

Hintergrund: Subunit beta of interleukin 12 (IL12B), also known as interleukin 12B, or interleukin-12 subunit p40, is a subunit of human interleukin 12. It is mapped to 5q33.3. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease.

Synonyms: Interleukin-12 subunit beta

Gen-ID: 64546

Pathways: JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation