SRY Antikörper (Middle Region)

Produktnummer ABIN5518959

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SRY in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SRY Antikörper (Middle Region) (ABIN5518959)

Target: SRY (Sex Determining Region Y (SRY))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SRY Antikörper

Bindungsspezifität: AA 90-130, Middle Region

Verwendungszweck: Anti-SRY Antibody Picoband®

Sequenz: ISKQLGYQWK MLTEAEKWPF FQEAQKLQAM HREKYPNYKY R

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SRY Antibody Picoband® (ABIN5518959). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SRY.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human
1. Biason-Lauber A, Konrad D, Meyer M, DeBeaufort C, Schoenle EJ (May 2009). "Ovaries and female phenotype in a girl with 46,XY karyotype and mutations in the CBX2 gene". Am. J. Hum. Genet. 84 (5): 658-63. 2. Margarit E, Coll MD, Oliva R, Gómez D, Soler A, Ballesta F (January 2000). "SRY gene transferred to the long arm of the X chromosome in a Y-positive XX true hermaphrodite". Am. J. Med. Genet. 90 (1): 25-8. 3. Polanco JC, Koopman P (February 2007). "Sry and the hesitant beginnings of male development". Dev. Biol. 302 (1): 13-24.

Kommentare:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu SRY

Target: SRY (Sex Determining Region Y (SRY))

Andere Bezeichnung: SRY

Hintergrund:

Synonyms: Sex-determining region Y protein,Testis-determining factor,SRY,TDF,

Tissue Specificity: Plasma. Isoform 1 and isoform 2 are widely expressed. Isoform 1 is the predominant form in spleen. .

Background: This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome), translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

Molekulargewicht: 26 kDa

Gen-ID: 6736

UniProt: Q05066