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GAS6 Antikörper (AA 488-660)

GAS6 Reaktivität: Human, Maus, Ratte WB, IHC, ICC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5518836
  • Target Alle GAS6 Antikörper anzeigen
    GAS6 (Growth Arrest-Specific 6 (GAS6))
    Bindungsspezifität
    • 14
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 488-660
    Reaktivität
    • 45
    • 21
    • 14
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 43
    • 4
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 45
    • 3
    • 2
    Polyklonal
    Konjugat
    • 23
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GAS6 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 13
    • 12
    • 12
    • 8
    • 6
    • 5
    • 4
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
    Verwendungszweck
    Anti-GAS 6/GAS6 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-GAS 6/GAS6 Antibody Picoband® (ABIN5518836). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human GAS 6 recombinant protein (Position: M488-S660). Human GAS 6 shares 79.7% and 81.4% amino acid (aa) sequence identity with mouse and rat GAS 6, respectively.
    Isotyp
    IgG
    Top Product
    Discover our top product GAS6 Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Mark MR, Chen J, Hammonds RG, Sadick M, Godowsk PJ (Apr 1996). "Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl". J. Biol. Chem. 271 (16): 9785-9. 2. Nagata K, Ohashi K, Nakano T, Arita H, Zong C, Hanafusa H, Mizuno K (Nov 1996). "Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases". J. Biol. Chem. 271 (47): 30022-7.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    GAS6 (Growth Arrest-Specific 6 (GAS6))
    Andere Bezeichnung
    GAS6 (GAS6 Produkte)
    Hintergrund

    Synonyms: Growth arrest-specific protein 6,GAS-6,AXL receptor tyrosine kinase ligand,GAS6,AXLLG,

    Tissue Specificity: Plasma. Isoform 1 and isoform 2 are widely expressed. Isoform 1 is the predominant form in spleen. .

    Background: Growth arrest-specific 6, also known as GAS6, is a human gene coding for the Gas6 protein. It is similar to the Protein S with the same domain organization and 43 % amino acid identity. It was originally found as a gene upregulated by growth arrested fibroblasts. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia.

    Molekulargewicht
    75 kDa
    Gen-ID
    2621
    UniProt
    Q14393
    Pathways
    RTK Signalweg, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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