ARNTL Antikörper (AA 58-156)

Produktnummer ABIN5518808

Produktdetails anti-ARNTL Antikörper

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Bindungsspezifität: AA 58-156

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARNTL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Aryl hydrocarbon receptor nuclear translocator-like protein 1(ARNTL) detection. Tested with WB in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Aryl hydrocarbon receptor nuclear translocator-like protein 1(ARNTL) detection. Tested with WB in Human.
Gene Name: aryl hydrocarbon receptor nuclear translocator like
Protein Name: Aryl hydrocarbon receptor nuclear translocator-like protein 1

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human BMAL1/ARNTL recombinant protein (Position: H58-D156). Human BMAL1/ARNTL shares 99% and 98% amino acid (aa) sequence identity with mouse and rat BMAL1/ARNTL, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu ARNTL

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Andere Bezeichnung: ARNTL (ARNTL Produkte)

Synonyme: BMAL1 antikoerper, BMAL1c antikoerper, JAP3 antikoerper, MOP3 antikoerper, PASD3 antikoerper, TIC antikoerper, bHLHe5 antikoerper, Bmal1 antikoerper, ARNTL antikoerper, xBmal1 antikoerper, arntl antikoerper, Arnt3 antikoerper, BMAL1b antikoerper, bmal1b' antikoerper, aryl hydrocarbon receptor nuclear translocator like antikoerper, aryl hydrocarbon receptor nuclear translocator-like antikoerper, aryl hydrocarbon receptor nuclear translocator like S homeolog antikoerper, ARNTL antikoerper, Arntl antikoerper, arntl.S antikoerper, arntl antikoerper

Hintergrund: Aryl hydrocarbon receptor nuclear translocator-like protein 1 is protein that in humans is encoded by the ARNTL gene. The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms: Arntl | bHLHe5 | BMAL 1 | BMAL1 | BMAL1c | CG8727 PA | cycle | JAP 3 | JAP3 | MGC47515 | MOP 3 | MOP3 | PASD 3 | PASD3 | TIC | O00327

Gen-ID: 406

UniProt: O00327

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effekt